Fundamentals of Immunology: Death by Friendly Fire

Course Overview

What does this course tell?
(Please note that the following overview content is from the original platform)
Course 3 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.This is the third leg of the journey through the defenses your body uses to keep you healthy. In the first course we learned about innate immunity and B cell function. In the second course we studied T cell function and coordination of the immune response. Fundamentals of Immunology: Death by Friendly Fire introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. After describing the form, function, origin and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline. What You’ll Learn: A survey of immune cells and how they attack pathogens, with emphasis on the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity. The inflammatory response and mechanisms of generating tolerance, presented in sequence to emphasize the decision making involved in controlling attacks. A survey of autoimmune disease, their characteristics, cause and treatment. Survey of hypersensitivity reactions, including allergy, anaphylaxis, anemias, granulomas, and a variety of skin responses. This is accompanied by identification, prevention and treatment. The final discussion of preventing transplant rejection is preceded by a detailed unit on antibody technology and the methods of testing for incompatibility.

We considered the value of this course from many aspects, and finally summarized it for you from two aspects: skills and knowledge, and the people who benefit from it:
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What skills and knowledge will you acquire during this course?
During the course "Fundamentals of Immunology: Death by Friendly Fire," students will acquire the following skills and knowledge:
1. Understanding of immune cells and their role in attacking pathogens, with a focus on the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity.
2. Knowledge of the inflammatory response and the mechanisms involved in generating tolerance, presented in a sequential manner to highlight the decision-making process in controlling attacks.
3. Familiarity with autoimmune diseases, including their characteristics, causes, and treatment options.
4. Understanding of hypersensitivity reactions, such as allergies, anaphylaxis, anemias, granulomas, and various skin responses. This includes identification, prevention, and treatment strategies.
5. Knowledge of preventing transplant rejection, preceded by a detailed unit on antibody technology and methods of testing for incompatibility.
Who will benefit from this course?
This course on Fundamentals of Immunology: Death by Friendly Fire will benefit individuals who are interested in or working in the field of immunology, biology, medicine, or related healthcare professions.
Specifically, this course will be beneficial for:
1. Students and researchers in the field of immunology: This course provides a comprehensive understanding of the adaptive and innate immune systems, including the functions of immune cells, tissues, and organs. It covers topics such as antibody generation, gene rearrangement, affinity maturation, and antibody structure. This knowledge is essential for those pursuing a career in immunology research or related fields.
2. Healthcare professionals: Doctors, nurses, and other healthcare professionals will benefit from this course as it covers topics such as the mechanism of inducing apoptosis, antibody-directed cell-mediated cytotoxicity, and the inflammatory response. This knowledge is crucial for understanding how the immune system attacks pathogens and how to control immune responses in various diseases.
3. Biotechnology professionals: Professionals working in the biotechnology industry, particularly in the field of antibody technology, will find this course valuable. It provides a detailed unit on antibody technology and methods of testing for incompatibility, which are essential for developing and testing therapeutic antibodies.
4. Individuals interested in autoimmune diseases and allergies: The course includes a survey of autoimmune diseases, their characteristics, causes, and treatment. It also covers hypersensitivity reactions, including allergies and anaphylaxis, along with their identification, prevention, and treatment. Individuals interested in understanding these conditions or working in related fields will find this course informative.
5. Transplant surgeons and immunologists: The course concludes with a discussion on preventing transplant rejection, which is of particular interest to transplant surgeons and immunologists. It provides insights into the immune response against transplanted organs and the methods used to prevent rejection.